| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Shawnee | 1 | 32,680 | 31,299 | 0.63% | 847 | 39 | City |
| Tecumseh | 2 | 6,419 | 6,308 | 0.27% | 427 | 15 | City |
| McLoud | 3 | 4,606 | 4,350 | 0.92% | 256 | 18 | City |
| Bethel Acres | 4 | 3,355 | 3,052 | 1.64% | 119 | 28 | Town |
| Maud | 5 | 879 | 865 | 0.23% | 838 | 1 | City |
| Earlsboro | 6 | 624 | 597 | 0.65% | 67 | 9 | Town |
| Johnson | 7 | 469 | 452 | 0.43% | 105 | 4 | Town |
| Asher | 8 | 375 | 366 | 0.27% | 488 | 1 | Town |
| Wanette | 9 | 318 | 310 | 0.32% | 194 | 2 | Town |
| St. Louis | 10 | 133 | 130 | 0% | 14 | 9 | Town |
| Brooksville | 11 | 74 | 71 | 0% | 25 | 3 | Town |
| Macomb | 12 | 25 | 25 | 0% | 281 | 0 | Town |
Shawnee is the largest city in Pottawatomie County, with a population of 32,680.
Macomb is the smallest city in Pottawatomie County, with a population of 25.
There are 12 cities in Pottawatomie County, Oklahoma.