| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Guymon | 1 | 12,146 | 12,899 | -1.02% | 1,570 | 8 | City |
| Hooker | 2 | 1,700 | 1,795 | -0.93% | 1,537 | 1 | City |
| Goodwell | 3 | 915 | 951 | -0.65% | 416 | 2 | Town |
| Texhoma | 4 | 822 | 860 | -0.72% | 1,282 | 1 | Town |
| Tyrone | 5 | 738 | 729 | 0.27% | 1,749 | 0 | Town |
| Optima | 6 | 322 | 337 | -0.62% | 604 | 1 | Town |
| Hardesty | 7 | 199 | 204 | -0.5% | 884 | 0 | Town |
Guymon is the largest city in Texas County, with a population of 12,146.
Hardesty is the smallest city in Texas County, with a population of 199.
There are 7 cities in Texas County, Oklahoma.