| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Guymon | 1 | 12,091 | 12,912 | -1.23% | 1,563 | 8 | City |
| Hooker | 2 | 1,686 | 1,798 | -1.17% | 1,524 | 1 | City |
| Goodwell | 3 | 908 | 948 | -0.77% | 413 | 2 | Town |
| Texhoma | 4 | 817 | 861 | -0.97% | 1,275 | 1 | Town |
| Tyrone | 5 | 748 | 728 | 0.4% | 1,773 | 0 | Town |
| Optima | 6 | 309 | 330 | -1.28% | 580 | 1 | Town |
| Hardesty | 7 | 194 | 203 | -1.02% | 862 | 0 | Town |
Guymon is the largest city in Texas County, with a population of 12,091.
Hardesty is the smallest city in Texas County, with a population of 194.
There are 7 cities in Texas County, Oklahoma.