South Illinois Cities

117 cities

City
Rank
County
2025 Pop. ↓
Carbondale1Jackson County21,393
Marion2Williamson County16,860
Mount Vernon3Jefferson County14,041
Herrin4Williamson County12,070
Harrisburg5Saline County7,713
West Frankfort6Franklin County7,073
Murphysboro7Jackson County6,883
Benton8Franklin County6,533
Carterville9Williamson County5,778
Metropolis10Massac County5,668
Du Quoin11Perry County5,610
Pinckneyville12Perry County4,952
Fairfield13Wayne County4,652
Anna14Union County4,038
Eldorado15Saline County3,521
Johnston City16Williamson County3,260
Christopher17Franklin County2,605
McLeansboro18Franklin County2,587
Cambria19Williamson County1,913
Sesser20Franklin County1,838
Ina21Jefferson County1,655
Jonesboro22Union County1,603
Carrier Mills23Saline County1,565
Crainville24Jackson County1,493
Zeigler25Franklin County1,458
Cairo26Alexander County1,452
De Soto27Jackson County1,368
Vienna28Johnson County1,341
Goreville29Johnson County1,058
Royalton30Franklin County1,031
Cobden31Union County1,012
Harrison32Jackson County975
Wayne City33Wayne County963
Energy34Williamson County941
Rosiclare35Hardin County939
Elkville36Jackson County812
Galatia37Saline County773
Hurst38Williamson County743
Brookport39Massac County675
West City40Franklin County633
Dongola41Union County625
Golconda42Pope County614
Cisne43Wayne County610
Bluford44Jefferson County600
Woodlawn45Jefferson County596
Mounds46Pulaski County590
Willisville47Perry County561
Pittsburg48Williamson County554
Ava49Jackson County537
Valier50Franklin County537
Tamaroa51Perry County527
Makanda52Jackson County525
Olive Branch53Alexander County506
Dahlgren54Hamilton County498
North City55Franklin County497
Creal Springs56Williamson County491
Thompsonville57Franklin County476
Mound City58Pulaski County468
Grand Tower59Jackson County463
Dix60Jefferson County454
Ullin61Pulaski County437
Waltonville62Jefferson County400
Buckner63Franklin County395
Karnak64Pulaski County391
Bonnie65Jefferson County361
Dowell66Jackson County361
Tamms67Alexander County356
Blairsville68Jackson County350
Cutler69Perry County348
Jeffersonville70Wayne County338
Joppa71Massac County323
Orient72Franklin County317
Hanaford73Franklin County312
Campbell Hill74Jackson County299
Alto Pass75Union County298
Belle Rive76Jefferson County298
Ewing77Franklin County292
Raleigh78Saline County271
Freeman Spur79Williamson County265
Olmsted80Pulaski County262
Opdyke81Jefferson County260
Crab Orchard82Williamson County241
East Cape Girardeau83Alexander County241
Bush84Jackson County236
Whiteash85Williamson County236
Vergennes86Jackson County231
Cave-In-Rock87Hardin County219
Cypress88Johnson County218
Stonefort89Saline County218
Elizabethtown90Hardin County216
McClure91Alexander County213
Buncombe92Johnson County206
Nason93Jefferson County197
Broughton94Hamilton County177
Spillertown95Williamson County175
Thebes96Alexander County174
Colp97Williamson County173
Gorham98Jackson County165
New Minden99Perry County165
Sims100Wayne County163
St. Johns101Jackson County156
New Burnside102Johnson County153
New Grand Chain103Massac County141
Pulaski104Pulaski County137
Mount Erie105Wayne County95
Eddyville106Pope County94
Belknap107Johnson County85
Johnsonville108Wayne County68
Unity109Alexander County68
Golden Gate110Wayne County58
Mulkeytown111Franklin County55
Muddy112Saline County54
Mill Creek113Pulaski County53
Belle Prairie City114Hamilton County48
Keenes115Wayne County48
Simpson116Johnson County44
Macedonia117Hamilton County29