9 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Vincennes | 1 | 16,380 | 16,758 | -0.38% | 2,197 | 7 | City |
| Bicknell | 2 | 2,982 | 3,033 | -0.27% | 2,204 | 1 | City |
| Oaktown | 3 | 580 | 580 | 0% | 2,132 | 0 | Town |
| Monroe City | 4 | 487 | 492 | -0.2% | 1,810 | 0 | Town |
| Bruceville | 5 | 450 | 447 | 0.22% | 1,312 | 0 | Town |
| Wheatland | 6 | 391 | 393 | 0% | 954 | 0 | Town |
| Sandborn | 7 | 359 | 362 | 0% | 921 | 0 | Town |
| Edwardsport | 8 | 278 | 283 | -0.36% | 989 | 0 | Town |
| Decker | 9 | 198 | 198 | 0% | 1,053 | 0 | Town |
Vincennes is the largest city in Knox County, with a population of 16,380.
Decker is the smallest city in Knox County, with a population of 198.
There are 9 cities in Knox County, Indiana.