| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Madison | 1 | 12,273 | 12,327 | -0.25% | 1,420 | 9 | City |
| Hanover | 2 | 3,890 | 3,740 | 0.62% | 1,751 | 2 | Town |
| Dupont | 3 | 340 | 339 | 0% | 337 | 1 | Town |
| Brooksburg | 4 | 71 | 72 | 0% | 696 | 0 | Town |
Madison is the largest city in Jefferson County, with a population of 12,273.
Brooksburg is the smallest city in Jefferson County, with a population of 71.
There are 4 cities in Jefferson County, Indiana.