| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Seymour | 1 | 22,567 | 22,056 | 0.52% | 1,699 | 13 | City |
| Brownstown | 2 | 3,165 | 3,021 | 0.35% | 1,955 | 2 | Town |
| Crothersville | 3 | 1,509 | 1,504 | 0.2% | 1,301 | 1 | Town |
| Medora | 4 | 642 | 641 | 0.16% | 2,112 | 0 | Town |
Seymour is the largest city in Jackson County, with a population of 22,567.
Medora is the smallest city in Jackson County, with a population of 642.
There are 4 cities in Jackson County, Indiana.