| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Harrisburg | 1 | 7,844 | 8,251 | -0.98% | 1,186 | 7 | City |
| Eldorado | 2 | 3,542 | 3,735 | -1.03% | 1,415 | 3 | City |
| Carrier Mills | 3 | 1,579 | 1,664 | -1% | 1,307 | 1 | Village |
| Galatia | 4 | 777 | 820 | -1.02% | 398 | 2 | Village |
| Raleigh | 5 | 273 | 288 | -1.09% | 138 | 2 | Village |
| Stonefort | 6 | 219 | 223 | -0.45% | 151 | 1 | Village |
| Muddy | 7 | 54 | 58 | -1.82% | 178 | 0 | Village |
Harrisburg is the largest city in Saline County, with a population of 7,844.
Muddy is the smallest city in Saline County, with a population of 54.
There are 7 cities in Saline County, Illinois.