| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Clinton | 1 | 23,965 | 24,444 | -0.35% | 673 | 36 | City |
| DeWitt | 2 | 5,728 | 5,517 | 0.42% | 921 | 6 | City |
| Camanche | 3 | 4,551 | 4,569 | -0.13% | 513 | 9 | City |
| Wheatland | 4 | 759 | 780 | -0.52% | 1,322 | 1 | City |
| Grand Mound | 5 | 598 | 618 | -0.5% | 320 | 2 | City |
| Delmar | 6 | 538 | 545 | -0.19% | 704 | 1 | City |
| Lost Nation | 7 | 423 | 431 | -0.47% | 560 | 1 | City |
| Charlotte | 8 | 385 | 389 | -0.26% | 674 | 1 | City |
| Calamus | 9 | 344 | 354 | -0.58% | 698 | 0 | City |
| Goose Lake | 10 | 249 | 249 | 0% | 752 | 0 | City |
| Low Moor | 11 | 238 | 248 | -0.83% | 437 | 1 | City |
| Andover | 12 | 103 | 106 | -0.96% | 575 | 0 | City |
Clinton is the largest city in Clinton County, with a population of 23,965.
Andover is the smallest city in Clinton County, with a population of 103.
There are 12 cities in Clinton County, Iowa.