Cape Girardeau County, St. Francois County, Butler County, Howell County, Scott County, Stoddard County, Dunklin County, Crawford County, Perry County, New Madrid County, Dent County, Pemiscot County, Madison County, Mississippi County, Bollinger County, Ripley County, Wayne County, Iron County, Oregon County, Shannon County, Reynolds County, and Carter County are the counties generally considered part of Southeast Missouri.