Southeast Missouri Cities

164 cities

City
Rank
County
2025 Pop. ↓
Cape Girardeau1Cape Girardeau County41,076
Farmington2St. Francois County19,520
Poplar Bluff3Butler County16,150
Jackson4Cape Girardeau County16,048
Sikeston5Scott County16,010
West Plains6Howell County12,830
Kennett7Dunklin County10,046
Park Hills8St. Francois County8,730
Perryville9Perry County8,552
Dexter10Stoddard County7,877
Bonne Terre11St. Francois County6,391
Caruthersville12Pemiscot County5,077
Desloge13St. Francois County4,838
Salem14Dent County4,747
Fredericktown15Madison County4,617
Scott City16Scott County4,455
Charleston17Mississippi County4,406
Malden18Dunklin County3,481
Cuba19Crawford County3,246
Chaffee20Scott County3,009
East Prairie21Mississippi County2,839
Mountain View22Howell County2,678
Portageville23New Madrid County2,672
New Madrid24New Madrid County2,554
Willow Springs25Howell County2,227
Hayti26Pemiscot County2,222
Thayer27Oregon County1,910
Piedmont28Wayne County1,862
Bernie29Stoddard County1,830
Doniphan30Ripley County1,782
Bloomfield31Stoddard County1,737
Steele32Pemiscot County1,654
Bourbon33Crawford County1,525
Senath34Dunklin County1,495
Campbell35Dunklin County1,493
Steelville36Crawford County1,439
Ironton37Iron County1,437
Marble Hill38Bollinger County1,381
Advance39Stoddard County1,332
Indian Lake40Crawford County1,250
Bismarck41St. Francois County1,219
Oran42Scott County1,206
Leadwood43St. Francois County1,150
Winona44Shannon County996
Clarkton45Dunklin County937
Benton46Scott County921
Lilbourn47New Madrid County893
Miner48Mississippi County889
Puxico49Stoddard County866
Van Buren50Carter County780
Leadington51St. Francois County762
Doe Run52St. Francois County759
Ellington53Reynolds County759
Gideon54New Madrid County703
Alton55Oregon County702
Bertrand56Mississippi County700
Pilot Knob57Iron County685
Morley58Scott County683
Morehouse59New Madrid County671
Viburnum60Iron County656
Iron Mountain Lake61Iron County639
Gordonville62Cape Girardeau County631
Arcadia63Iron County604
Holcomb64Dunklin County585
Doolittle65Dent County578
Birch Tree66Shannon County566
Shakertowne67Bollinger County565
Kelso68Scott County552
Eminence69Shannon County534
Cardwell70Dunklin County527
Parma71New Madrid County499
Hornersville72Dunklin County498
Matthews73New Madrid County493
Qulin74Butler County467
Bell City75Stoddard County460
Hayti Heights76Pemiscot County454
Naylor77Ripley County441
Greenville78Wayne County437
Ellsinore79Carter County419
Oak Grove Village80Crawford County402
Essex81Stoddard County393
Millersville82Cape Girardeau County387
Arbyrd83Dunklin County385
Delta84Cape Girardeau County380
Marston85New Madrid County358
Fairdealing86Ripley County345
Altenburg87Cape Girardeau County335
Leasburg88Crawford County316
Cooter89Pemiscot County312
Neelyville90Butler County310
Fisk91Butler County308
Bunker92Reynolds County296
Junction City93Madison County286
West Sullivan94Crawford County279
Wardell95Pemiscot County275
Williamsville96Wayne County271
Cobalt97Madison County263
Dutchtown98Cape Girardeau County260
Risco99New Madrid County258
Howardville100New Madrid County249
Frohna101Perry County246
Annapolis102Iron County244
Oak Ridge103Cape Girardeau County238
Grandin104Carter County231
New Hamburg105Scott County231
Perkins106Scott County225
Shawneetown107Cape Girardeau County215
Mine La Motte108Madison County208
Blodgett109Scott County206
Wyatt110Mississippi County205
Koshkonong111Oregon County196
Pomona112Howell County196
Marquand113Madison County190
Whiting114Mississippi County190
Sedgewickville115Bollinger County189
Cherokee Pass116Madison County186
Vanduser117Scott County186
Anniston118Mississippi County178
Holland119Pemiscot County176
Centerville120Reynolds County162
Burfordville121Cape Girardeau County161
Mill Spring122Wayne County157
Diehlstadt123Mississippi County156
Canalou124New Madrid County144
Haywood City125Cape Girardeau County135
Brandsville126Howell County128
Des Arc127Iron County128
Denton128Dunklin County124
Miramiguoa Park129Crawford County123
Frankclay130St. Francois County100
Dudley131Stoddard County98
Pocahontas132Cape Girardeau County97
Wortham133St. Francois County96
Allenville134Cape Girardeau County95
Longtown135Bollinger County93
Montier136Shannon County91
Hunter137Carter County87
Zalma138Bollinger County86
Whitewater139Cape Girardeau County85
Pascola140Pemiscot County79
Deering141Pemiscot County76
Old Appleton142Cape Girardeau County75
Wilson City143Mississippi County74
Frisbee144Dunklin County72
Tallapoosa145New Madrid County70
Broseley146Butler County69
Homestown147Pemiscot County67
White Oak148Dunklin County64
Bragg City149Pemiscot County59
Lithium150Bollinger County59
Glen Allen151Bollinger County57
Penermon152Stoddard County51
South Fork153Howell County51
Grayridge154Stoddard County50
Biehle155Bollinger County46
Rives156Dunklin County42
New Wells157Cape Girardeau County41
Commerce158Scott County40
St. Cloud159Crawford County40
Catron160New Madrid County36
Hayward161New Madrid County27
Knob Lick162St. Francois County24
North Lilbourn163New Madrid County19
Oxly164Ripley County11

About Southeast Missouri

Sources

  1. City and Town Population Totals: 2020-2024