Southeast Missouri Cities

There are 156 cities in Missouri in the Southeast region.

156 Rows

City
Rank
County
2024 Pop.
Cape Girardeau1Cape Girardeau County40,750
Farmington2Ste. Genevieve County18,568
Poplar Bluff3Butler County16,108
Sikeston4Mississippi County16,026
Jackson5Cape Girardeau County15,840
West Plains6Douglas County12,730
Kennett7Dunklin County9,993
Park Hills8St. Francois County8,811
Perryville9Bollinger County8,488
Dexter10Stoddard County7,856
Caruthersville11Pemiscot County5,125
Salem12Crawford County4,736
Fredericktown13Madison County4,546
Charleston14Mississippi County4,440
Scott City15Cape Girardeau County4,350
Malden16Dunklin County3,465
Licking17Dent County3,055
Chaffee18Cape Girardeau County3,015
East Prairie19Mississippi County2,847
Portageville20New Madrid County2,710
Mountain View21Howell County2,689
New Madrid22New Madrid County2,574
Hayti23Pemiscot County2,255
Thayer24Oregon County1,905
Piedmont25Reynolds County1,852
Bernie26Dunklin County1,827
Doniphan27Carter County1,807
Bloomfield28Stoddard County1,732
Steele29Dunklin County1,678
Campbell30Dunklin County1,500
Senath31Dunklin County1,495
Ironton32Iron County1,441
Marble Hill33Bollinger County1,373
Advance34Bollinger County1,330
Bismarck35Iron County1,240
Oran36Cape Girardeau County1,206
Leadwood37St. Francois County1,164
Winona38Oregon County991
Clarkton39Dunklin County939
Benton40Scott County921
Lilbourn41New Madrid County908
Miner42Mississippi County896
Puxico43Bollinger County857
Doe Run44St. Francois County769
Leadington45St. Francois County767
Ellington46Reynolds County766
Van Buren47Carter County764
Gideon48New Madrid County712
Alton49Oregon County706
Bertrand50Mississippi County696
Morley51Scott County686
Pilot Knob52Iron County685
Morehouse53Mississippi County681
Viburnum54Iron County655
Iron Mountain Lake55Iron County647
Gordonville56Cape Girardeau County626
Arcadia57Iron County605
Holcomb58Dunklin County587
Birch Tree59Oregon County561
Kelso60Scott County549
Eminence61Shannon County527
Shakertowne62Bollinger County527
Cardwell63Dunklin County523
Parma64New Madrid County507
Hornersville65Dunklin County498
Matthews66New Madrid County498
Brewer67Randolph County494
Summersville68Shannon County476
Hayti Heights69Pemiscot County468
Qulin70Butler County468
Bell City71Bollinger County455
Naylor72Butler County448
Greenville73Wayne County438
Ellsinore74Butler County424
Essex75Stoddard County397
Arbyrd76Dunklin County387
Delta77Cape Girardeau County375
Raymondville78Texas County374
Irondale79Iron County368
Fairdealing80Ripley County367
Marston81New Madrid County363
Millersville82Cape Girardeau County362
Altenburg83Cape Girardeau County338
Cooter84Pemiscot County314
Neelyville85Butler County312
Fisk86Butler County310
Bunker87Dent County296
Junction City88Madison County281
Wardell89Pemiscot County278
Williamsville90Butler County271
Cobalt91Madison County262
Risco92New Madrid County259
Howardville93New Madrid County252
Annapolis94Iron County245
Dutchtown95Cape Girardeau County243
Frohna96Cape Girardeau County243
Oak Ridge97Cape Girardeau County238
Grandin98Carter County230
Mine La Motte99Madison County217
Pomona100Howell County217
New Hamburg101Scott County216
Wyatt102Mississippi County211
Perkins103Scott County210
Blodgett104Mississippi County205
Edgar Springs105Dent County203
Shawneetown106Cape Girardeau County201
Koshkonong107Howell County199
Cherokee Pass108Madison County190
Marquand109Bollinger County188
Sedgewickville110Bollinger County187
Vanduser111Scott County187
Anniston112Mississippi County177
Whiting113Mississippi County177
Holland114Pemiscot County176
Centerville115Reynolds County162
Diehlstadt116Mississippi County156
Mill Spring117Wayne County156
Burfordville118Cape Girardeau County150
Canalou119New Madrid County147
Haywood City120Cape Girardeau County135
Caledonia121Iron County133
Brandsville122Howell County129
Des Arc123Iron County128
Denton124Dunklin County116
Wortham125St. Francois County108
Dudley126Stoddard County100
Allenville127Cape Girardeau County94
Pocahontas128Cape Girardeau County94
Hunter129Carter County92
Longtown130Bollinger County90
Montier131Oregon County85
Whitewater132Bollinger County85
Pascola133Pemiscot County81
Zalma134Bollinger County80
Wilson City135Mississippi County74
Tallapoosa136New Madrid County72
Deering137Pemiscot County71
Old Appleton138Cape Girardeau County71
Homestown139Pemiscot County70
Frisbee140Dunklin County68
Broseley141Butler County64
Bragg City142Pemiscot County61
Glen Allen143Bollinger County60
White Oak144Dunklin County60
Grayridge145Stoddard County55
Lithium146Bollinger County55
Penermon147Stoddard County48
Biehle148Bollinger County43
Rives149Dunklin County41
Commerce150Scott County40
New Wells151Cape Girardeau County38
Catron152New Madrid County37
Hayward153New Madrid County34
Oxly154Ripley County24
Knob Lick155Ste. Genevieve County22
North Lilbourn156New Madrid County20
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Missouri Cities by Region