Southeast Missouri Cities

164 cities

City
Rank
County
2025 Pop. ↓
Cape Girardeau1Cape Girardeau County41,076
Farmington2St. Francois County19,520
Poplar Bluff3Butler County16,150
Jackson4Cape Girardeau County16,048
Sikeston5Scott County16,010
West Plains6Howell County12,830
Kennett7Dunklin County10,046
Park Hills8St. Francois County8,730
Perryville9Perry County8,552
Dexter10Stoddard County7,877
Bonne Terre11St. Francois County6,391
Caruthersville12Pemiscot County5,077
Desloge13St. Francois County4,838
Salem14Dent County4,747
Fredericktown15Madison County4,617
Scott City16Scott County4,455
Charleston17Mississippi County4,406
Malden18Dunklin County3,481
Cuba19Crawford County3,246
Chaffee20Scott County3,009
East Prairie21Mississippi County2,839
Mountain View22Howell County2,678
Portageville23New Madrid County2,672
New Madrid24New Madrid County2,554
Willow Springs25Howell County2,227
Hayti26Pemiscot County2,222
Thayer27Oregon County1,910
Piedmont28Wayne County1,862
Bernie29Stoddard County1,830
Doniphan30Ripley County1,782
Bloomfield31Stoddard County1,737
Steele32Pemiscot County1,654
Bourbon33Crawford County1,525
Senath34Dunklin County1,495
Campbell35Dunklin County1,493
Steelville36Crawford County1,439
Ironton37Iron County1,437
Marble Hill38Bollinger County1,381
Advance39Stoddard County1,332
Indian Lake40Crawford County1,240
Bismarck41St. Francois County1,219
Oran42Scott County1,206
Leadwood43St. Francois County1,150
Winona44Shannon County996
Clarkton45Dunklin County937
Benton46Scott County921
Lilbourn47New Madrid County893
Doe Run48St. Francois County892
Miner49Mississippi County889
Puxico50Stoddard County866
Van Buren51Carter County780
Leadington52St. Francois County762
Ellington53Reynolds County759
Gideon54New Madrid County703
Alton55Oregon County702
Bertrand56Mississippi County700
Pilot Knob57Iron County685
Morley58Scott County683
Morehouse59New Madrid County671
Viburnum60Iron County656
Iron Mountain Lake61Iron County639
Gordonville62Cape Girardeau County631
Arcadia63Iron County604
Holcomb64Dunklin County585
Doolittle65Dent County578
Birch Tree66Shannon County566
Kelso67Scott County552
Eminence68Shannon County534
Cardwell69Dunklin County527
Parma70New Madrid County499
Hornersville71Dunklin County498
Matthews72New Madrid County493
Shakertowne73Bollinger County480
Qulin74Butler County467
Bell City75Stoddard County460
Hayti Heights76Pemiscot County454
Naylor77Ripley County441
Greenville78Wayne County437
Ellsinore79Carter County419
Oak Grove Village80Crawford County402
Essex81Stoddard County393
Arbyrd82Dunklin County385
Delta83Cape Girardeau County380
Marston84New Madrid County358
Millersville85Cape Girardeau County352
Altenburg86Cape Girardeau County335
Fairdealing87Ripley County319
Leasburg88Crawford County316
Cooter89Pemiscot County312
Neelyville90Butler County310
Fisk91Butler County308
Bunker92Reynolds County296
Junction City93Madison County286
Dutchtown94Cape Girardeau County279
West Sullivan95Crawford County279
Wardell96Pemiscot County275
Williamsville97Wayne County271
Cobalt98Madison County263
Risco99New Madrid County258
Howardville100New Madrid County249
Frohna101Perry County246
Annapolis102Iron County244
Oak Ridge103Cape Girardeau County238
Grandin104Carter County231
Burfordville105Cape Girardeau County213
Blodgett106Scott County206
Wyatt107Mississippi County205
Pomona108Howell County202
Koshkonong109Oregon County196
New Hamburg110Scott County195
Marquand111Madison County190
Shawneetown112Cape Girardeau County190
Sedgewickville113Bollinger County189
Vanduser114Scott County186
Anniston115Mississippi County178
Holland116Pemiscot County176
Perkins117Scott County172
Denton118Dunklin County164
Centerville119Reynolds County162
Mill Spring120Wayne County157
Diehlstadt121Mississippi County156
Wortham122St. Francois County146
Canalou123New Madrid County144
Haywood City124Cape Girardeau County135
Brandsville125Howell County128
Des Arc126Iron County128
Mine La Motte127Madison County124
Miramiguoa Park128Crawford County123
Cherokee Pass129Madison County114
White Oak130Dunklin County104
Montier131Shannon County103
Fremont132Carter County99
Dudley133Stoddard County98
Pocahontas134Cape Girardeau County97
Allenville135Cape Girardeau County95
Longtown136Bollinger County93
Knob Lick137St. Francois County91
Zalma138Bollinger County89
Whiting139Mississippi County88
Hayward140New Madrid County85
Whitewater141Cape Girardeau County85
Grayridge142Stoddard County79
Pascola143Pemiscot County79
Old Appleton144Cape Girardeau County75
Frisbee145Dunklin County74
Wilson City146Mississippi County74
Tallapoosa147New Madrid County70
Homestown148Pemiscot County67
Deering149Pemiscot County66
Bragg City150Pemiscot County59
Glen Allen151Bollinger County57
Frankclay152St. Francois County55
Penermon153Stoddard County51
Lithium154Bollinger County50
Hunter155Carter County43
Rives156Dunklin County42
Commerce157Scott County40
St. Cloud158Crawford County40
South Fork159Howell County40
Thomasville160Oregon County40
Catron161New Madrid County36
Broseley162Butler County31
North Lilbourn163New Madrid County19
Biehle164Bollinger County12

About Southeast Missouri

Sources

  1. City and Town Population Totals: 2020-2024