Upstate South Carolina Cities

140 cities

City
Rank
County
2025 Pop. ↓
Greenville1Greenville County73,964
Greer2Greenville County50,113
Spartanburg3Spartanburg County39,328
Anderson4Anderson County30,316
Mauldin5Greenville County30,166
Simpsonville6Greenville County30,109
Easley7Pickens County28,620
Taylors8Greenville County23,352
Greenwood9Greenwood County22,456
Wade Hampton10Greenville County21,131
Five Forks11Greenville County19,705
Clemson12Pickens County17,894
Berea13Anderson County16,656
Fountain Inn14Greenville County14,702
Gantt15Greenville County14,288
Powdersville16Anderson County13,348
Parker17Greenville County12,725
Gaffney18Cherokee County12,312
Boiling Springs19Spartanburg County11,934
Travelers Rest20Greenville County9,371
Laurens21Laurens County9,238
Seneca22Oconee County9,167
Sans Souci23Greenville County8,085
Clemson University24Anderson County7,771
Clinton25Laurens County7,770
Homeland Park26Anderson County7,740
Union27Union County7,705
Centerville28Anderson County7,375
Valley Falls29Spartanburg County7,305
Welcome30Anderson County7,274
Lyman31Spartanburg County7,044
Piedmont32Greenville County5,612
Central33Pickens County5,358
Abbeville34Abbeville County4,863
Woodruff35Spartanburg County4,797
Duncan36Spartanburg County4,675
Whitney37Spartanburg County4,668
Belton38Anderson County4,623
Saxon39Spartanburg County4,358
Williamston40Anderson County4,329
Walhalla41Oconee County4,277
Roebuck42Spartanburg County4,246
Hilltop43Spartanburg County4,066
Northlake44Anderson County4,050
Honea Path45Anderson County3,953
Southern Shops46Spartanburg County3,878
Keowee Key47Oconee County3,824
Wellford48Spartanburg County3,809
Pendleton49Anderson County3,762
Golden Grove50Anderson County3,486
Inman51Spartanburg County3,410
Pickens52Pickens County3,385
Dunean53Greenville County3,366
Liberty54Pickens County3,270
Arkwright55Spartanburg County3,236
East Gaffney56Cherokee County2,944
Arcadia57Spartanburg County2,899
Landrum58Spartanburg County2,834
Ben Avon59Spartanburg County2,701
Pacolet60Spartanburg County2,603
Westminster61Oconee County2,453
Tigerville62Greenville County2,324
Cowpens63Spartanburg County2,298
Slater-Marietta64Greenville County2,205
Camp Croft65Spartanburg County2,116
Watts Mills66Laurens County2,108
Ninety Six67Greenwood County2,052
Mayo68Spartanburg County2,008
Blacksburg69Cherokee County1,929
Reidville70Spartanburg County1,878
Judson71Greenville County1,836
City View72Greenville County1,784
Monarch Mill73Union County1,755
Calhoun Falls74Abbeville County1,734
Ware Shoals75Greenwood County1,702
Utica76Oconee County1,695
Fairforest77Spartanburg County1,609
Arial78Pickens County1,552
Conestee79Greenville County1,515
Pelzer80Anderson County1,441
Joanna81Laurens County1,373
Lake Secession82Abbeville County1,287
Drayton83Spartanburg County1,264
La France84Anderson County1,239
Cateechee85Anderson County1,216
Due West86Abbeville County1,216
Iva87Anderson County1,203
Buffalo88Union County1,132
Sandy Springs89Anderson County1,091
Clifton90Spartanburg County1,067
The Cliffs Valley91Greenville County1,052
West Pelzer92Anderson County1,034
Chesnee93Spartanburg County949
Inman Mills94Spartanburg County932
Jonesville95Union County802
Gray Court96Laurens County782
Campobello97Spartanburg County776
Chickasaw Point98Anderson County754
Six Mile99Pickens County751
Norris100Pickens County747
Modoc101McCormick County698
Fair Play102Oconee County546
South Union103Anderson County479
Startex104Spartanburg County476
Mount Carmel105McCormick County420
Cross Hill106Laurens County419
Cokesbury107Abbeville County416
West Union108Oconee County392
Enoree109Spartanburg County385
Newry110Oconee County383
Lockhart111Union County362
Antreville112Abbeville County323
Donalds113Abbeville County322
Carlisle114Union County312
Promised Land115Abbeville County290
Pauline116Spartanburg County286
Dacusville117Pickens County272
Glendale118Spartanburg County241
Central Pacolet119Cherokee County240
Glenn Springs120Spartanburg County234
Starr121Anderson County177
Hodges122Greenwood County164
Bradley123Greenwood County161
Waterloo124Laurens County156
Converse125Spartanburg County149
Mountville126Laurens County142
Parksville127McCormick County131
Salem128Oconee County125
Lowndesville129Abbeville County123
Tamassee130Oconee County102
Gramling131Spartanburg County99
Princeton132Abbeville County98
Fingerville133Spartanburg County90
Troy134Greenwood County88
Plum Branch135McCormick County84
Ware Place136Anderson County63
Caesars Head137Greenville County52
Cherokee Falls138Cherokee County38
Longcreek139Oconee County36
Clarks Hill140McCormick County2

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