22 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Carroll township | 1 | 5,260 | 5,237 | -0.1% | 153 | 34.27 | Township |
| Newport township | 2 | 4,470 | 4,422 | 0.16% | 277 | 16.12 | Township |
| Wheatfield township | 3 | 3,189 | 3,200 | -0.22% | 153 | 20.80 | Township |
| Marysville | 4 | 2,685 | 2,654 | 0.22% | 1,150 | 2.33 | Borough |
| Saville township | 5 | 2,610 | 2,598 | -0.08% | 57 | 45.92 | Township |
| Centre township | 6 | 2,532 | 2,516 | -0.04% | 84 | 30.02 | Township |
| Spring township | 7 | 2,307 | 2,294 | -0.09% | 81 | 28.64 | Township |
| Rye township | 8 | 2,241 | 2,262 | -0.4% | 87 | 25.72 | Township |
| Juniata township | 9 | 1,536 | 1,531 | -0.13% | 74 | 20.88 | Township |
| Newport | 10 | 1,500 | 1,485 | 0.2% | 4,983 | 0.30 | Borough |
| Duncannon | 11 | 1,444 | 1,471 | -0.34% | 3,548 | 0.41 | Borough |
| Watts township | 12 | 1,247 | 1,234 | 0.08% | 105 | 11.88 | Township |
| Buffalo township | 13 | 1,236 | 1,226 | 0% | 61 | 20.10 | Township |
| Bloomfield | 14 | 1,225 | 1,215 | 0.16% | 2,005 | 0.61 | Borough |
| Liverpool township | 15 | 1,046 | 1,035 | 0.1% | 50 | 20.91 | Township |
| Greenwood township | 16 | 1,042 | 1,033 | 0% | 42 | 25.06 | Township |
| Southwest Madison township | 17 | 1,025 | 1,020 | -0.1% | 37 | 27.36 | Township |
| Liverpool | 18 | 970 | 960 | 0.21% | 1,101 | 0.88 | Borough |
| Millerstown | 19 | 698 | 688 | 0.29% | 826 | 0.84 | Borough |
| Blain | 20 | 229 | 226 | 0.44% | 720 | 0.32 | Borough |
| Landisburg | 21 | 225 | 220 | 0.45% | 3,169 | 0.07 | Borough |
| New Buffalo | 22 | 125 | 124 | 0% | 2,119 | 0.06 | Borough |
Carroll township is the largest city in Perry County, with a population of 5,260.
New Buffalo is the smallest city in Perry County.
There are 22 cities in Perry County, Pennsylvania.