28 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Bradford | 1 | 7,378 | 7,833 | -1.22% | 2,218 | 3 | City |
| Bradford | 2 | 4,584 | 4,794 | -0.84% | 82 | 56 | Township |
| Foster | 3 | 3,830 | 4,036 | -0.96% | 83 | 46 | Township |
| Kane | 4 | 3,414 | 3,626 | -1.22% | 2,181 | 2 | Borough |
| Bradford | 5 | 2,794 | 2,832 | -0.43% | 73 | 38 | Township |
| Keating | 6 | 2,626 | 2,723 | -0.72% | 27 | 98 | Township |
| Eldred | 7 | 2,547 | 2,600 | -0.82% | 104 | 25 | Township |
| Lafayette | 8 | 2,113 | 1,761 | 1.44% | 30 | 71 | Township |
| Port Allegany | 9 | 2,009 | 2,134 | -1.23% | 1,133 | 2 | Borough |
| Eldred | 10 | 1,949 | 1,993 | -0.31% | 137 | 14 | Township |
| Wetmore | 11 | 1,575 | 1,619 | -0.69% | 20 | 79 | Township |
| Otto | 12 | 1,454 | 1,519 | -0.62% | 42 | 35 | Township |
| Smethport | 13 | 1,353 | 1,435 | -1.17% | 805 | 2 | Borough |
| Eldred | 14 | 1,334 | 1,393 | -0.74% | 35 | 39 | Township |
| Eldred | 15 | 1,245 | 1,275 | -0.24% | 27 | 47 | Township |
| Foster Brook | 16 | 1,023 | 1,115 | -1.54% | 325 | 3 | CDP |
| University Pittsburgh Bradford | 17 | 1,015 | 723 | 7.18% | 9,398 | 0 | CDP |
| Mount Jewett | 18 | 804 | 851 | -1.11% | 334 | 2 | Borough |
| Ceres | 19 | 794 | 841 | -1.12% | 20 | 40 | Township |
| Eldred | 20 | 716 | 766 | -1.38% | 818 | 1 | Borough |
| Eldred | 21 | 716 | 709 | 0.14% | 32 | 22 | Township |
| Annin | 22 | 713 | 707 | 0.56% | 22 | 33 | Township |
| Eldred | 23 | 567 | 586 | -0.53% | 16 | 36 | Township |
| Lewis Run | 24 | 545 | 579 | -1.27% | 298 | 2 | Borough |
| Norwich | 25 | 490 | 506 | -0.2% | 5 | 95 | Township |
| Corydon | 26 | 274 | 285 | -1.08% | 4 | 73 | Township |
| Sergeant | 27 | 141 | 148 | -0.7% | 2 | 80 | Township |
| Rew | 28 | 122 | 138 | -3.94% | 124 | 1 | CDP |
Bradford is the largest city in McKean County, with a population of 7,378.
Rew is the smallest city in McKean County, with a population of 122.
There are 28 cities in McKean County, Pennsylvania.