There are 18 cities in St. Lucie County, Florida.
Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Population | 2020 Population | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Port St. Lucie | 1 | 257,756 | 206,815 | 5.2% | 2,162 | 119.2 | City |
| Fort Pierce | 2 | 49,962 | 47,610 | 1.19% | 2,068 | 24.2 | City |
| Palm City | 3 | 26,430 | 25,038 | 0.91% | 1,907 | 13.9 | CDP |
| Stuart | 4 | 20,059 | 17,541 | 3.24% | 2,819 | 7.1 | City |
| Lakewood Park | 5 | 14,585 | 14,227 | 1.62% | 2,188 | 6.7 | CDP |
| Jensen Beach | 6 | 12,727 | 13,592 | 0.58% | 1,825 | 7.0 | CDP |
| Indian River Estates | 7 | 7,089 | 6,542 | 0.88% | 1,277 | 5.6 | CDP |
| Fort Pierce North | 8 | 6,526 | 7,199 | 0.05% | 1,541 | 4.2 | CDP |
| River Park | 9 | 6,347 | 7,139 | 1.29% | 2,699 | 2.4 | CDP |
| White City | 10 | 5,790 | 5,091 | 2.62% | 1,163 | 5.0 | CDP |
| Okeechobee | 11 | 5,719 | 5,251 | 2.09% | 1,410 | 4.1 | City |
| Fort Pierce South | 12 | 5,356 | 4,468 | 0.39% | 2,066 | 2.6 | CDP |
| Hutchinson Island South | 13 | 4,037 | 5,025 | -2.02% | 938 | 4.3 | CDP |
| Cypress Quarters | 14 | 1,501 | 1,517 | 1.42% | 562 | 2.7 | CDP |
| Rio | 15 | 1,441 | 705 | 2.42% | 3,812 | 0.4 | CDP |
| St. Lucie Village | 16 | 603 | 610 | -0.33% | 671 | 0.9 | Town |
| Ocean Breeze | 17 | 433 | 308 | 7.71% | 2,624 | 0.2 | Town |
| Yeehaw Junction | 18 | 116 | 244 | -7.2% | 62 | 1.9 | CDP |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Port St. Lucie is the largest city in St. Lucie County.
Yeehaw Junction is the smallest city in St. Lucie County.
There are 18 cities in St. Lucie County, Florida.