6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Pleasanton | 1 | 11,590 | 10,683 | 1.59% | 1,291 | 9 | City |
| Jourdanton | 2 | 4,650 | 4,242 | 1.77% | 1,279 | 4 | City |
| Lytle | 3 | 3,428 | 2,912 | 3.1% | 697 | 5 | City |
| Poteet | 4 | 3,055 | 2,805 | 1.66% | 1,531 | 2 | City |
| Charlotte | 5 | 1,642 | 1,532 | 1.36% | 805 | 2 | City |
| Christine | 6 | 371 | 338 | 1.64% | 216 | 2 | Town |
Pleasanton is the largest city in Atascosa County, with a population of 11,590.
Christine is the smallest city in Atascosa County, with a population of 371.
There are 6 cities in Atascosa County, Texas.