7 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Colorado City | 1 | 3,894 | 3,990 | -0.54% | 730 | 5 | City |
| Colorado City | 2 | 3,894 | 3,999 | -0.54% | 730 | 5 | City |
| Lake Colorado City | 3 | 982 | 602 | 2.72% | 127 | 8 | CDP |
| Loraine | 4 | 494 | 506 | -0.6% | 475 | 1 | Town |
| Loraine | 5 | 494 | 507 | -0.6% | 475 | 1 | Town |
| Westbrook | 6 | 204 | 202 | 0% | 483 | 0 | City |
| Westbrook | 7 | 204 | 203 | 0% | 483 | 0 | City |
Colorado City is the largest city in Mitchell County, with a population of 3,894.
Westbrook is the smallest city in Mitchell County, with a population of 204.
There are 7 cities in Mitchell County, Texas.