2 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Quanah | 1 | 2,128 | 2,286 | -1.21% | 612 | 3 | City |
| Chillicothe | 2 | 520 | 555 | -1.14% | 509 | 1 | City |
Quanah is the largest city in Hardeman County, with a population of 2,128.
Chillicothe is the smallest city in Hardeman County, with a population of 520.
There are 2 cities in Hardeman County, Texas.