2 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Quanah | 1 | 2,154 | 2,286 | -1.24% | 620 | 3 | City |
| Chillicothe | 2 | 526 | 555 | -1.13% | 515 | 1 | City |
Quanah is the largest city in Hardeman County, with a population of 2,154.
Chillicothe is the smallest city in Hardeman County, with a population of 526.
There are 2 cities in Hardeman County, Texas.