6 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| London | 1 | 10,709 | 10,268 | 0.83% | 1,275 | 8.40 | City |
| West Jefferson | 2 | 4,710 | 4,155 | 2.41% | 475 | 9.92 | Village |
| Plain City | 3 | 4,467 | 4,144 | 1.48% | 1,624 | 2.75 | Village |
| Mount Sterling | 4 | 2,089 | 1,941 | 1.46% | 1,238 | 1.69 | Village |
| South Solon | 5 | 326 | 325 | 0% | 1,387 | 0.23 | Village |
| Midway | 6 | 269 | 269 | 0% | 1,035 | 0.26 | Village |
London is the largest city in Madison County, with a population of 10,709.
Midway is the smallest city in Madison County.
There are 6 cities in Madison County, Ohio.