| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Plantersville | 1 | 532 | 457 | 2.31% | 269 | 2 | City |
| Bedias | 2 | 421 | 360 | 2.43% | 380 | 1 | City |
| Iola | 3 | 362 | 314 | 2.26% | 351 | 1 | City |
| Anderson | 4 | 221 | 194 | 1.84% | 432 | 1 | City |
| Todd Mission | 5 | 128 | 115 | 1.59% | 65 | 2 | City |
Plantersville is the largest city in Grimes County, with a population of 532.
Todd Mission is the smallest city in Grimes County, with a population of 128.
There are 5 cities in Grimes County, Texas.