| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Quanah | 1 | 2,062 | 2,282 | -1.67% | 593 | 3 | City |
| Chillicothe | 2 | 504 | 557 | -1.75% | 494 | 1 | City |
Quanah is the largest city in Hardeman County, with a population of 2,062.
Chillicothe is the smallest city in Hardeman County, with a population of 504.
There are 2 cities in Hardeman County, Texas.