| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Woodville | 1 | 2,344 | 2,335 | 0.21% | 745 | 3 | Town |
| Colmesneil | 2 | 552 | 538 | 0.55% | 276 | 2 | City |
| Chester | 3 | 269 | 271 | 0% | 171 | 2 | Town |
Woodville is the largest city in Tyler County, with a population of 2,344.
Chester is the smallest city in Tyler County, with a population of 269.
There are 3 cities in Tyler County, Texas.