| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Nacogdoches | 1 | 32,622 | 32,049 | 0.38% | 1,182 | 28 | City |
| Garrison | 2 | 842 | 792 | 1.08% | 717 | 1 | City |
| Cushing | 3 | 589 | 559 | 0.86% | 429 | 1 | City |
| Appleby | 4 | 555 | 545 | 0.36% | 258 | 2 | City |
| Chireno | 5 | 379 | 371 | 0.26% | 202 | 2 | City |
Nacogdoches is the largest city in Nacogdoches County, with a population of 32,622.
Chireno is the smallest city in Nacogdoches County, with a population of 379.
There are 5 cities in Nacogdoches County, Texas.