3 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Macon | 1 | 2,386 | 2,558 | -1.4% | 623 | 3.83 | City |
| Brooksville | 2 | 865 | 914 | -1.14% | 544 | 1.59 | Town |
| Shuqualak | 3 | 371 | 401 | -1.59% | 329 | 1.13 | Town |
Macon is the largest city in Noxubee County, with a population of 2,386.
Shuqualak is the smallest city in Noxubee County.
There are 3 cities in Noxubee County, Mississippi.