| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Quitman | 1 | 1,899 | 2,050 | -1.35% | 367 | 5 | City |
| Stonewall | 2 | 824 | 876 | -1.08% | 310 | 3 | Town |
| Enterprise | 3 | 470 | 499 | -1.05% | 192 | 2 | Town |
| Shubuta | 4 | 393 | 405 | -0.51% | 163 | 2 | Town |
| Pachuta | 5 | 193 | 205 | -1.03% | 79 | 2 | Town |
Quitman is the largest city in Clarke County, with a population of 1,899.
Pachuta is the smallest city in Clarke County, with a population of 193.
There are 5 cities in Clarke County, Mississippi.