| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Carthage | 1 | 4,859 | 4,891 | -0.1% | 523 | 9 | City |
| Walnut Grove | 2 | 512 | 507 | 0.2% | 317 | 2 | Town |
| Lena | 3 | 158 | 158 | 0% | 95 | 2 | Town |
Carthage is the largest city in Leake County, with a population of 4,859.
Lena is the smallest city in Leake County, with a population of 158.
There are 3 cities in Leake County, Mississippi.