| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Louisville | 1 | 5,888 | 6,064 | -0.56% | 390 | 15 | City |
| Noxapater | 2 | 381 | 387 | -0.52% | 378 | 1 | Town |
Louisville is the largest city in Winston County, with a population of 5,888.
Noxapater is the smallest city in Winston County, with a population of 381.
There are 2 cities in Winston County, Mississippi.