| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Iuka | 1 | 3,090 | 3,135 | -0.48% | 319 | 10 | City |
| Belmont | 2 | 1,810 | 1,859 | -0.55% | 383 | 5 | Town |
| Burnsville | 3 | 855 | 863 | -0.23% | 179 | 5 | Town |
| Tishomingo | 4 | 363 | 373 | -0.55% | 426 | 1 | Town |
Iuka is the largest city in Tishomingo County, with a population of 3,090.
Tishomingo is the smallest city in Tishomingo County, with a population of 363.
There are 4 cities in Tishomingo County, Mississippi.