9 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Springfield | 1 | 171,315 | 169,158 | 0.21% | 2,059 | 83 | City |
| Republic | 2 | 22,636 | 18,903 | 2.83% | 1,413 | 16 | City |
| Willard | 3 | 6,762 | 6,372 | 0.97% | 1,118 | 6 | City |
| Strafford | 4 | 2,918 | 2,567 | 2.06% | 887 | 3 | City |
| Fair Grove | 5 | 1,643 | 1,589 | 0.55% | 516 | 3 | City |
| Ash Grove | 6 | 1,526 | 1,517 | 0.13% | 1,149 | 1 | City |
| Pleasant Hope | 7 | 702 | 671 | 0.72% | 462 | 2 | City |
| Walnut Grove | 8 | 639 | 648 | -0.16% | 1,029 | 1 | City |
| Springfield | 9 | 315 | 303 | 0.64% | 10 | 33 | Township |
Springfield is the largest city in Greene County, with a population of 171,315.
Springfield is the smallest city in Greene County, with a population of 315.
There are 9 cities in Greene County, Missouri.