8 cities
| City | Rank | 2026 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Noel | 1 | 2,221 | 2,127 | 0.73% | 1,097 | 2 | City |
| Anderson | 2 | 2,114 | 2,039 | 0.62% | 930 | 2 | City |
| Goodman | 3 | 1,357 | 1,201 | 1.95% | 1,023 | 1 | City |
| Southwest City | 4 | 1,004 | 919 | 1.41% | 686 | 1 | Town |
| Pineville | 5 | 868 | 792 | 1.52% | 264 | 3 | City |
| Jane | 6 | 422 | 358 | 2.68% | 142 | 3 | Town |
| Lanagan | 7 | 384 | 374 | 0.52% | 409 | 1 | Town |
| Ginger Blue | 8 | 35 | 34 | 0% | 134 | 0 | Village |
Noel is the largest city in McDonald County, with a population of 2,221.
Ginger Blue is the smallest city in McDonald County, with a population of 35.
There are 8 cities in McDonald County, Missouri.