16 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Annual Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Mount Pleasant | 1 | 97,903 | 91,225 | 1.38% | 1,972 | 50 | Town |
| James Island | 2 | 12,066 | 11,658 | 0.68% | 2,543 | 5 | Town |
| Hollywood | 3 | 5,543 | 5,297 | 0.89% | 236 | 24 | Town |
| Isle Palms | 4 | 4,384 | 4,348 | 0.16% | 988 | 4 | City |
| Ravenel | 5 | 2,701 | 2,553 | 1.12% | 205 | 13 | Town |
| Seabrook Island | 6 | 2,135 | 2,055 | 0.76% | 360 | 6 | Town |
| Folly Beach | 7 | 2,085 | 2,079 | 0.05% | 167 | 13 | City |
| Kiawah Island | 8 | 1,949 | 2,014 | -0.66% | 174 | 11 | Town |
| Sullivan's Island | 9 | 1,938 | 1,898 | 0.41% | 776 | 2 | Town |
| Awendaw | 10 | 1,479 | 1,409 | 0.96% | 85 | 17 | Town |
| Meggett | 11 | 1,455 | 1,394 | 0.83% | 80 | 18 | Town |
| Lincolnville | 12 | 1,209 | 1,154 | 0.92% | 1,007 | 1 | Town |
| Edisto Beach | 13 | 1,062 | 1,029 | 0.66% | 499 | 2 | Town |
| McClellanville | 14 | 626 | 606 | 0.64% | 281 | 2 | Town |
| Adams Run | 15 | 559 | 772 | 7.09% | 398 | 1 | CDP |
| Rockville | 16 | 139 | 136 | 0.72% | 328 | 0 | Town |
Mount Pleasant is the largest city in Charleston County, with a population of 97,903.
Rockville is the smallest city in Charleston County, with a population of 139.
There are 16 cities in Charleston County, South Carolina.