There are 26 cities in Pickens County, South Carolina.
Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Population | 2020 Population | Annual Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Greenville | 1 | 73,394 | 71,114 | 0.78% | 2,440 | 30.1 | City |
| Easley | 2 | 27,503 | 23,035 | 4.23% | 2,091 | 13.2 | City |
| Clemson | 3 | 17,866 | 17,753 | 0.16% | 2,258 | 7.9 | City |
| Berea | 4 | 16,499 | 15,104 | 0.97% | 2,143 | 7.7 | CDP |
| Parker | 5 | 12,638 | 12,175 | 0.69% | 1,848 | 6.8 | CDP |
| Powdersville | 6 | 12,458 | 9,436 | 7.69% | 906 | 13.8 | CDP |
| Seneca | 7 | 9,105 | 8,856 | 0.69% | 1,105 | 8.2 | City |
| Clemson University | 8 | 7,253 | 5,329 | 7.69% | 3,426 | 2.1 | CDP |
| Welcome | 9 | 7,234 | 7,743 | 0.57% | 1,568 | 4.6 | CDP |
| Central | 10 | 5,340 | 5,268 | 0.34% | 1,643 | 3.3 | Town |
| Pendleton | 11 | 3,709 | 3,499 | 1.42% | 756 | 4.9 | Town |
| Pickens | 12 | 3,388 | 3,400 | -0.09% | 1,108 | 3.1 | City |
| Dunean | 13 | 3,386 | 3,099 | -0.62% | 2,159 | 1.6 | CDP |
| Liberty | 14 | 3,289 | 3,367 | -0.6% | 678 | 4.8 | City |
| Slater-Marietta | 15 | 2,203 | 2,098 | 0.09% | 511 | 4.3 | CDP |
| Judson | 16 | 1,850 | 1,412 | -0.8% | 2,354 | 0.8 | CDP |
| City View | 17 | 1,754 | 1,607 | 1.68% | 4,521 | 0.4 | CDP |
| Utica | 18 | 1,682 | 1,761 | 0.84% | 1,486 | 1.1 | CDP |
| Arial | 19 | 1,618 | 2,158 | -3.92% | 355 | 4.6 | CDP |
| La France | 20 | 1,156 | 856 | 7.63% | 892 | 1.3 | CDP |
| Cateechee | 21 | 1,135 | 738 | 7.69% | 2,221 | 0.5 | CDP |
| Sandy Springs | 22 | 1,018 | 974 | 7.61% | 354 | 2.9 | CDP |
| Six Mile | 23 | 752 | 758 | -0.27% | 369 | 2.0 | Town |
| Norris | 24 | 747 | 747 | 0% | 396 | 1.9 | Town |
| Dacusville | 25 | 254 | 307 | 7.63% | 116 | 2.2 | CDP |
| Caesars Head | 26 | 49 | 53 | 6.52% | 33 | 1.5 | CDP |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Greenville is the largest city in Pickens County.
Caesars Head is the smallest city in Pickens County.
There are 26 cities in Pickens County, South Carolina.