Note: As defined by the US Census Bureau, a city's official boundaries often extend miles beyond the city itself and may even cross county lines. As such, several thousand US cities officially exist in two or more counties (and therefore appear on multiple counties' lists of cities.)
City | Rank | 2024 Pop. | 2020 Pop. | Change | Density (/mi²) | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Columbia | 1 | 144,489 | 136,195 | 1.46% | 1,045 | 138.3 | City |
| Lexington | 2 | 25,343 | 23,653 | 1.69% | 2,117 | 12.0 | Town |
| St. Andrews | 3 | 22,145 | 21,355 | 0.54% | 3,605 | 6.1 | CDP |
| West Columbia | 4 | 18,581 | 17,519 | 1.45% | 1,982 | 9.4 | City |
| Seven Oaks | 5 | 15,940 | 16,743 | 0.36% | 2,083 | 7.7 | CDP |
| Cayce | 6 | 13,627 | 13,758 | -0.24% | 807 | 16.9 | City |
| Oak Grove | 7 | 11,567 | 12,040 | 0.79% | 1,526 | 7.6 | CDP |
| Red Bank | 8 | 10,698 | 9,971 | 0.73% | 853 | 12.5 | CDP |
| White Knoll | 9 | 8,382 | 7,476 | 7.68% | 1,370 | 6.1 | CDP |
| Lake Murray Richland | 10 | 7,152 | 6,672 | 1.69% | 1,289 | 5.5 | CDP |
| Springdale | 11 | 2,713 | 2,739 | -0.26% | 1,003 | 2.7 | Town |
| South Congaree | 12 | 2,388 | 2,374 | 0.13% | 726 | 3.3 | Town |
| Chapin | 13 | 1,938 | 1,817 | 1.57% | 979 | 2.0 | Town |
| Gaston | 14 | 1,639 | 1,611 | 0.43% | 308 | 5.3 | Town |
| Edmund | 15 | 1,340 | 930 | 7.63% | 196 | 6.8 | CDP |
| Swansea | 16 | 771 | 726 | 1.45% | 369 | 2.1 | Town |
| Fairview Crossroads | 17 | 686 | 665 | 7.69% | 120 | 5.7 | CDP |
| Pelion | 18 | 624 | 627 | -0.16% | 169 | 3.7 | Town |
| Gilbert | 19 | 621 | 577 | 1.8% | 229 | 2.7 | Town |
| Summit | 20 | 458 | 422 | 2% | 308 | 1.5 | Town |
Note: City markers shown outside the county boundary mean that a part of the city extends into this county, but is primarily located in an adjacent county.
Columbia is the largest city in Lexington County.
Summit is the smallest city in Lexington County.
There are 20 cities in Lexington County, South Carolina.